Autoclave Chamber Material: Stainless Steel vs Nickel-Clad Written by: Amit Gupta Current, state-of-the-art laboratory autoclave chambers are manufactured using stainless steel. In the past, autoclave manufacturers constructed sterilizers using nickel-clad, a highly corrosion-resistant material. The industry has shifted due to the rising cost of “cladding” over the last 10-15 years, heading in the direction of primarily 316L stainless steel. Why should you care? Because while stainless […] Tweet Like Share
How To Validate an Autoclave: Operational Qualification (OQ) Written by: Amit Gupta Every laboratory strives for consistency and repeatability in its sterilization processes. But this doesn’t come easily. In order to ensure your autoclave operates efficiently it’s critical that you validate the sterilization process and verify that the equipment is working safely and properly. This is known as Operational Qualification (OQ), and it’s one of the most […] Tweet Like Share
Canopy Hood Designs: An Important Consideration for Your Lab Written by: Scott Mechler You have a lot of choices when it comes to ventilation solutions for your autoclave and some are better than others. Canopy hoods are an optimal solution for handling odors, steam moisture and low-levels of chemical vapors.  The following are guidelines from the National Institute for Health for the design of autoclave door canopy hoods. The […] Tweet Like Share
Lab Ventilation Systems for Your Autoclave Written by: Scott Mechler The need for a proper lab ventilation system when running a sterilization cycle in your laboratory autoclave cannot be understated. Ventilation for autoclaves assures that the various odors, steam moisture and low-levels of chemical vapors that come from the sterilization process do not escape further into the laboratory setting. When not regulated correctly with an […] Tweet Like Share
Autoclaves for BSL-3 Facilities—Part 3: Effluent Decontamination Systems Written by: Scott Mechler This is the final article of a three-part series describing BSL-3 autoclaves, also commonly known as biocontainment sterilizers. These types of sterilizers are essential in handling microbes that can lead to serious or potentially lethal disease through inhalation. Links to our first and second article can be found here: Part 1: The Bio-Seal Part 2: Autoclave […] Tweet Like Share
Why You Need a Cloud-Connected Autoclave Written by: Mike Peters Autoclave recordkeeping is an essential component of sterilization best practices. Industry standards stipulate that time, temperature, and pressure must be recorded for every cycle that is run, and those records must be maintained for three years. And today, thanks to the birth of the Internet of Labs (IoL) and the creation of cloud-connected autoclaves, researchers, […] Tweet Like Share
How To Validate an Autoclave: Installation Qualification (IQ) Written by: Amit Gupta There is an array of qualification tests that can be conducted to validate an autoclave. Many laboratories validate autoclaves by simply using biological indicators (BI’s). For some labs, however, a simple validation with BI’s is not enough and a more elaborate validation process must be followed. These labs typically require installation, operation, and performance qualifications […] Tweet Like Share
Autoclaves for BSL-3 Facilities—Part 2: Autoclave Door Safety Written by: Scott Mechler This is the second of three articles describing BSL-3 autoclaves, also commonly known as biocontainment sterilizers. These types of sterilizers are essential in handling microbes that can lead to serious or potentially lethal disease through inhalation. In this article we review the important aspects of the autoclave door design that are essential for every BSL-3 […] Tweet Like Share
Autoclaves for BSL-3 Facilities—Part 1: The Bio-Seal Written by: Scott Mechler This is the first of three articles describing BSL-3 autoclaves, also commonly known as biocontainment sterilizers. These types of sterilizers are essential in handling microbes that can lead to serious or potentially lethal disease through inhalation. In this article we explore the importance of the bio-seal, a feature that must be incorporated into a BSL-3 […] Tweet Like Share
7 Common Causes for Failure of a Bowie-Dick Test Written by: Amit Gupta Sterilization departments have one of the most important responsibilities within a healthcare facility — ensuring that all surgical instruments and other reusable equipment are sterilized and safe to use during upcoming procedures. Without these services, operations at hospitals and ambulatory surgery centers would grind to a halt. In laboratory settings (especially in ones that carry […] Tweet Like Share
12.10.25 Introducing SterilSteam Sampler, The Steam Condensate Sampler for AAMI ST108 Compliance → Released in 2023, AAMI/ANSI ST108 establishes water quality requirements for water used in the cleaning, rinsing, disinfection, and sterilization of reusable medical devices. In addition to these requirements, ST108 mandates quarterly testing of steam condensate quality to ensure incoming steam does not stain instruments or pose a risk to patient safety. To help healthcare facilities […]
11.6.25 AAMI ST108 & Critical Water for Autoclaves: What ASCs Need to Know → A major step forward in patient safety, ANSI/AAMI ST108 establishes new minimum water quality requirements for water used in the cleaning, rinsing, disinfection, and sterilization of reusable medical devices. Despite providing guidance on water quality management for sterile processing, ST108 has also created confusion, especially regarding test protocols, water treatment, and critical water requirements. In […]
10.20.25 What Is an Autoclave Machine Really Used for? [Applications, Costs & More] → Autoclave machines are mission-critical equipment in a variety of industries, from healthcare to biotech, ensuring equipment and materials are sterilized and safe for use. Whether you’re considering purchasing an autoclave for a new facility, replacing a broken one, or expanding your current sterilization capacity, understanding the ins and outs of autoclave technology is key to […]